The vasodilator action of formaldehyde

Vasodilator action of guanethidine.

The mutagenic action of formaldehyde on bacteria.

Rapoport (1946), Kaplan (1948), and Auerbach (1949) found formaldehyde highly mutagenic for Drosophila when administered with its food. Auerbach (1949), however, observed negative results when Drosophila was exposed to formaldehyde vapor and concluded that formaldehyde acts indirectly through chemical changes brought about in food constituents. Dickey, Cleland, and Lotz (1949) found formaldehyd...

Action of Formaldehyde on Microorganisms. Iii. Bactericidal Action of Sublethal Concentrations of Formaldehyde on Aerobacter Aerogenes.

Neely, W. Brock (The Dow Chemical Co., Midland, Mich.). Action of formaldehyde on microorganisms. III. Bactericidal action of sublethal concentrations of formaldehyde on Aerobacter aerogenes. J. Bacteriol. 86:445-448. 1963.-Bacteriostatic concentrations of formaldehyde were found to be bactericidal during the initial growth period. This bactericidal activity was due to the primary induction of ...

Enhancement of coronary vasodilator action of adenosine triphosphate by dipyridamole.

It has been reported that previously administered dipyridamole intensifies the coronary vasodilator action of adenosine compounds. In the present study, a combination of dipyridamole and ATP at doses that alone are ineffective was examined for its effect on the coronary sinus blood flow. In 10 anesthetized dogs, heart rate, arterial blood pressure, cardiac output, and coronary sinus blood flow ...

Mechanisms of action of OPC-28326, a selective hindlimb vasodilator.

The unique cardiovascular profile of OPC-28326 [4-(N-methyl-2-phenylethylamino)-1-(3, 5-dimethyl-4-propionylaminobenzoyl)piperidine hydrochloride monohydrate] provides insight into basic mechanisms of this new drug as determined by experiments in dogs and rats. In anesthetized open-chest dogs, an i.v. administration of a low dose (0.3 and 1.0 microg/kg) of OPC-28326 selectively increased femora...